BDBM728062 (Z)-4-([1,1''- biphen-yl]-2-yl)- 2-((1-acetyl-3- oxoindolin-2-yl- idene)methyl)-N- (1-(oxetan-3-yl)- piperidin-4-yl)- quinoline-6- carboxamide::US20250091994, Example 97
SMILES CC(=O)n8c(=Cc6cc(c1ccccc1c2ccccc2)c5cc(C(=O)NC4CCN(C3COC3)CC4)ccc5n6)c(=O)c7ccccc78
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728062
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 510nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
