BDBM728077 (Z)-2-((4-((3H- [1,2,3]triazolo [4,5-b]pyridin-3- yl)oxy)-6-(morph- oline-4-carbonyl)- quinolin-2-yl)- methylene)-1-acet- ylindolin-3-one::US20250091994, Example 112

SMILES CC(=O)n7c(=Cc5cc(On2nnc1cccnc12)c4cc(C(=O)N3CCOCC3)ccc4n5)c(=O)c6ccccc67

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728077   

LigandPNGBDBM728077((Z)-2-((4-((3H- [1,2,3]triazolo [4,5-b]pyridin-3- ...)
Affinity DataIC50: 550nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent