BDBM728125 (Z)-1-acetyl-2- ((6-(morpholine- 4-carbonyl)-4- (1H-pyrazol-4- yl)quinolin-2-yl)- methylene)indolin- 3-one::US20250091994, Example 170
SMILES CC(=O)n6c(=Cc4cc(c1cn[nH]c1)c3cc(C(=O)N2CCOCC2)ccc3n4)c(=O)c5ccccc56
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728125
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 500nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
