BDBM728127 (Z)-1-acetyl-2- ((4-(2-methyl- 1,2,3,4-tetrahydro- isoquinolin-6-yl)- 6-(morpholine- 4-carbonyl)quin- olin-2-yl)meth- ylene)indolin-3- one::US20250091994, Example 173

SMILES CC(=O)n7c(=Cc5cc(c2ccc1CN(C)CCc1c2)c4cc(C(=O)N3CCOCC3)ccc4n5)c(=O)c6ccccc67

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728127   

LigandPNGBDBM728127((Z)-1-acetyl-2- ((4-(2-methyl- 1,2,3,4-tetrahydro-...)
Affinity DataIC50: 400nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent