BDBM728135 (Z)-1-acetyl-2-((4- (morpholinometh- yl)quinolin-2-yl)- methylene)indolin- 3-one::US20250091994, Example 181
SMILES CC(=O)n5c(=Cc3cc(CN1CCOCC1)c2ccccc2n3)c(=O)c4ccccc45
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728135
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 2.40E+3nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
