BDBM728146 (Z)-1-acetyl-2- ((4-(1-methyl- 1H-imidazol-4- yl)-6-(morpholine- 4-carbonyl)quin- olin-2-yl)meth- ylene)indolin-3- one::US20250091994, Example 192
SMILES CC(=O)n6c(=Cc4cc(c1cn(C)cn1)c3cc(C(=O)N2CCOCC2)ccc3n4)c(=O)c5ccccc56
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728146
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 800nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
