BDBM728154 (Z)-1-acetyl-2- ((4-(1-methyl-1H- pyrazol-4-yl)quin- azolin-2-yl)meth- ylene)indolin-3- one::US20250091994, Example 203
SMILES CC(=O)n5c(=Cc3nc(c1cnn(C)c1)c2ccccc2n3)c(=O)c4ccccc45
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728154
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 600nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
