BDBM728168 (2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- 4-(5-methanesulfonyl- pyrimidin-2-yl)-2,5- dimethylpiperazine-1- carboxamide::US20250092022, Compound 4

SMILES C[C@@H]1CN(c2ncc(S(C)(=O)=O)cn2)[C@@H](C)CN1C(=O)NC1CC2(C1)CN(Cc1ccccc1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728168   

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728168((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent