BDBM728174 2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-[5-(ethane- sulfonyl)pyrimidin-2-yl]- 2,5-dimethylpiperazine-1- carboxylate::US20250092022, Compound 11

SMILES CCS(=O)(=O)c1cnc(N2C[C@@H](C)N(C(=O)OC3CC4(C3)CN(Cc3ccccc3)C4)C[C@@H]2C)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728174   

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728174(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-[5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent