BDBM728189 2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-methane- sulfonylpyrimidin-2-yl)- 2,6-dimethylpiperazine-1- carboxylate::US20250092022, Compound 33

SMILES C[C@@H]1CN(c2ncc(S(C)(=O)=O)cn2)C[C@H](C)N1C(=O)OC1CC2(C1)CN(Cc1ccccc1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728189   

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728189(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent