BDBM728191 2-[(4-chlorophenyl) methyl]-2-azaspiro[3.3] heptan-6-yl (2R,5S)-4-(5- methanesulfonylpyrimidin- 2-yl)-2,5-dimethyl- piperazine-1-carboxylate::US20250092022, Compound 37

SMILES C[C@@H]1CN(c2ncc(S(C)(=O)=O)cn2)[C@@H](C)CN1C(=O)OC1CC2(C1)CN(Cc1ccc(Cl)cc1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728191   

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728191(2-[(4-chlorophenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent