BDBM728210 2-[(4-methylphenyl) methyl]-2-azaspiro[3.3] heptan-6-yl (2R,6S)-4-(5- methanesulfonylpyrimidin- 2-yl)-2,6-dimethyl- piperazine-1-carboxylate::US20250092022, Compound 61

SMILES Cc1ccc(CN2CC3(CC(OC(=O)N4[C@H](C)CN(c5ncc(S(C)(=O)=O)cn5)C[C@@H]4C)C3)C2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728210   

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728210(2-[(4-methylphenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent