BDBM728247 US20250092039, Compound 39

SMILES CCc%11c(F)ccc%12cc(O)cc(c%10ncc9c(N1CCC[C@@](C)(O)C1)nc(OCC8(CN7CCC(C)(CN6CCN(C5CCN(c4ccc3C(=O)N(C2CCC(=O)NC2=O)Cc3c4)CC5)CC6)CC7)CC8)nc9c%10F)c%11%12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728247   

LigandPNGBDBM728247(US20250092039, Compound 39)
Affinity DataIC50: 20nMAssay Description:Briefly, for the KRAS-G12V/RAF1 binding assay, 2 nM GppNHp-bound 6*His tagged KRAS-G12V proteins or 2 nM GDP-bound 6*His tagged KRAS-G12V proteins (f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent