BDBM729439 N-(5-(3-benzyl-1-((1r,4S)-4-((5-(trifluoromethyl)pyridin-2-yl)amino)cyclohexyl)ureido)-2-((S)-3,4-dimethylpiperazin-1-yl)phenyl)acrylamide::US20250100994, Compound YJZ1066

SMILES C=CC(=O)Nc4cc(N(C(=O)NCc1ccccc1)[C@@H]3CC[C@@H](Nc2ccc(C(F)(F)F)cn2)CC3)ccc4N5CCN(C)[C@@H](C)C5

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 729439   

TargetCyclin-dependent kinase 13(Human)
University of Michigan

US Patent
LigandPNGBDBM729439(N-(5-(3-benzyl-1-((1r,4S)-4-((5-(trifluoromethyl)p...)
Affinity DataIC50: 15nMAssay Description:The inhibitory activities of the test compound on the kinases were evaluated by LANCE Ultra assay, which was used for detecting ATP-dependent phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
University of Michigan

US Patent
LigandPNGBDBM729439(N-(5-(3-benzyl-1-((1r,4S)-4-((5-(trifluoromethyl)p...)
Affinity DataIC50: 32.5nMAssay Description:The inhibitory activities of the test compound on the kinases were evaluated by LANCE Ultra assay, which was used for detecting ATP-dependent phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent