BDBM730057 US12263171, Example 186A

SMILES COc1ccc2c(c1)nc(N)n1nc([C@@H]3CCCN(c4cn([C@@H](C)C(C)(C)O)nc4C)C3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 730057   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM730057(US12263171, Example 186A)
Affinity DataIC50: 0.400nMAssay Description:148 μL, (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM4001A) and 2 μL compounds of the invention to be tested (test compound) were transferred t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM730057(US12263171, Example 186A)
Affinity DataIC50: 462nMAssay Description:148 μL, (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM4001A) and 2 μL compounds of the invention to be tested (test compound) were transferred t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent