BDBM730300 US20250109156, Compound 6

SMILES CP(C)(=O)c1c4ccc2c(c[nH]c12)c3nc(ncc3C(F)(F)F)N[C@H]5CCCCN(CCCCNC4=O)C5

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 730300   

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical Co.

US Patent
LigandPNGBDBM730300(US20250109156, Compound 6)
Affinity DataIC50: 1.40nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetCyclin-Dependent Kinase 2 and Cyclin E1(Human)
Jiangsu Aosaikang Pharmaceutical Co.

US Patent
LigandPNGBDBM730300(US20250109156, Compound 6)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetCyclin-Dependent Kinase 9 and Cyclin T1(Human)
Jiangsu Aosaikang Pharmaceutical Co.

US Patent
LigandPNGBDBM730300(US20250109156, Compound 6)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent