BDBM731067 US20250122202, Example 104

SMILES CCN1CCN(c2ccc(Nc3nc(N[C@H]4CC[C@@H](CO)CC4)c4c(C(=O)c5ccc(F)cc5)c[nH]c4n3)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 731067   

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical

US Patent
LigandPNGBDBM731067(US20250122202, Example 104)
Affinity DataIC50: 2.72nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical

US Patent
LigandPNGBDBM731067(US20250122202, Example 104)
Affinity DataIC50: 11.4nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent