BDBM731092 6-cyano-4-(2-methoxyphenyl)-N-(6-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiazolo[4,5-b]pyrazin-2-yl)nicotinamide ::US20250122221, Compound 19

SMILES COc1ccccc1-c1cc(C#N)ncc1C(=O)Nc1nc2ncc(-c3ccc(=O)n(C)c3)nc2s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731092   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731092(6-cyano-4-(2-methoxyphenyl)-N-(6-(1-methyl-6-oxo-1...)
Affinity DataIC50: 100nMAssay Description:Brief introduction to the experimental principle: The N-terminal active peptide segment (MI-N899) of POLQ with ATPase activity was co-incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent