BDBM731134 N-(6-(5-cyanopyridin-2-yl)thiazolo[4,5-b]pyrazin-2-yl)-2''-chloro-5''-methoxy-6-methyl-[4,4-bipyridine]-3-carboxamide ::US20250122221, Compound 61

SMILES COc1cnc(Cl)cc1-c1cc(C)ncc1C(=O)Nc1nc2ncc(-c3ccc(C#N)cn3)nc2s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731134   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731134(N-(6-(5-cyanopyridin-2-yl)thiazolo[4,5-b]pyrazin-2...)
Affinity DataIC50: 100nMAssay Description:Brief introduction to the experimental principle: The N-terminal active peptide segment (MI-N899) of POLQ with ATPase activity was co-incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent