BDBM73125 US20250382276, Compound 14

SMILES COc1ccc(/C=C/C=C/C(=O)c2cccs2)cc1

InChI Key InChIKey=WVMHVWONHKSDGW-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 73125   

TargetAmine oxidase [flavin-containing] B(Human)
Amrita School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 73125BDBM73125(US20250382276, Compound 14)
Affinity DataKi:  4.5nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using varying levels of benzylamine as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Amrita School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 73125BDBM73125(US20250382276, Compound 14)
Affinity DataIC50: 36nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Amrita School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 73125BDBM73125(US20250382276, Compound 14)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using benzylamine as substrate measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Amrita Vishwa Vidyapeetham

US Patent
LigandChemical structure of BindingDB Monomer ID 73125BDBM73125(US20250382276, Compound 14)
Affinity DataIC50: 1.36E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Amrita Vishwa Vidyapeetham

US Patent
LigandChemical structure of BindingDB Monomer ID 73125BDBM73125(US20250382276, Compound 14)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed