BDBM731375 US12281118, Example 3

SMILES Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1Sc1ccnc(NC2CC2)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731375   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM731375(US12281118, Example 3)
Affinity DataIC50: 1nMAssay Description:(1) Preparing 1×Reaction Buffer according to the BPS Biosciences' Instructions for Use of the SHP2 enzyme. (2) Preparing a compound concentration...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent