BDBM731397 US12281118, Example 18

SMILES Cc1cc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2cnnc2c1Sc1ccnc(N)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731397   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM731397(US12281118, Example 18)
Affinity DataIC50: 24.6nMAssay Description:(1) Preparing 1×Reaction Buffer according to the BPS Biosciences' Instructions for Use of the SHP2 enzyme. (2) Preparing a compound concentration...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent