BDBM731418 (S)-3-((4-acrylamidophenyl)amino)-N-(2-(dimethylamino)-1-(tetrahydro-2H-pyran-4-yl)ethyl)-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide ::US12281126, Compound 209

SMILES C=CC(=O)Nc1ccc(Nc2n[nH]c3c2CN(C(=O)N[C@H](CN(C)C)C2CCOCC2)C3(C)C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 731418   

LigandPNGBDBM731418((S)-3-((4-acrylamidophenyl)amino)-N-(2-(dimethylam...)
Affinity DataIC50: 3.31E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM731418((S)-3-((4-acrylamidophenyl)amino)-N-(2-(dimethylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM731418((S)-3-((4-acrylamidophenyl)amino)-N-(2-(dimethylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent