BDBM731455 4-(3-chloro-5-fluorobenzyl)-N-(1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)piperidine-1-carboxamide ::US12268687, Compound 55

SMILES Cn1nc(NC(=O)N2CCC(Cc3cc(F)cc(Cl)c3)CC2)ccc1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 731455   

TargetStearoyl-CoA desaturase 5(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731455(4-(3-chloro-5-fluorobenzyl)-N-(1-methyl-6-oxo-1,6-...)
Affinity DataIC50: 20nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731455(4-(3-chloro-5-fluorobenzyl)-N-(1-methyl-6-oxo-1,6-...)
Affinity DataIC50: 160nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent