BDBM731506 6-(2-(4-(3,5-difluorobenzyl)piperidin-1-yl)oxazol-5-yl)-2-methylpyridazin-3(2H)-one ::US12268687, Compound 124

SMILES Cn1nc(-c2cnc(N3CCC(Cc4cc(F)cc(F)c4)CC3)o2)ccc1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 731506   

TargetStearoyl-CoA desaturase 5(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731506(6-(2-(4-(3,5-difluorobenzyl)piperidin-1-yl)oxazol-...)
Affinity DataIC50: 140nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731506(6-(2-(4-(3,5-difluorobenzyl)piperidin-1-yl)oxazol-...)
Affinity DataIC50: 2.60E+4nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent