BDBM731514 6-(5-(4-(3,5-difluorobenzyl)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2-methylpyridazin-3(2H)-one ::US12268687, Compound 121

SMILES Cn1nc(-c2nnc(N3CCC(Cc4cc(F)cc(F)c4)CC3)s2)ccc1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 731514   

TargetStearoyl-CoA desaturase 5(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731514(6-(5-(4-(3,5-difluorobenzyl)piperidin-1-yl)-1,3,4-...)
Affinity DataIC50: 10nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731514(6-(5-(4-(3,5-difluorobenzyl)piperidin-1-yl)-1,3,4-...)
Affinity DataIC50: 180nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent