BDBM731568 US12269804, Compound 15

SMILES Cc1nccc(N[C@H]2CC[C@@H](Oc3cc(N4CCOCC4)cc4ncc(=O)n(C)c34)CC2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731568   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM731568(US12269804, Compound 15)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent