BDBM731587 US12269804, Compound 11

SMILES Cn1c(=O)cnc2cc(C3=CCOCC3)cc(O[C@H]3CC[C@@H](Nc4ncccn4)CC3)c21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731587   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM731587(US12269804, Compound 11)
Affinity DataKi: <1nMAssay Description:To investigate the effect of DNA-PK inhibitors on HDR gene editing rates, BECs were electroporated with spCAS9 mRNA, NAV1.7 sgRNA and NAV1.7 Non-PAM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent