BDBM731683 (1R,3S)-1-[2,6-difluoro-4-[2- [3-(fluoromethyl)azetidin-1- yl]ethoxy]phenyl]-3- (fluoromethyl)-2-(2-fluoro-2- methyl-propyl)-1,3,4,9- tetrahydropyrido[3,4-b]indole::US20250114338, Example 135

SMILES CC(C)(F)CN1[C@H](CF)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cc(OCCN2CC(CF)C2)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731683   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731683((1R,3S)-1-[2,6-difluoro-4-[2- [3-(fluoromethyl)aze...)
Affinity DataEC50:  0.0970nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
8/22/2025
Entry Details
US Patent