BDBM731745 (1R,3R)-1-[4-(1- ethylazetidin-3-yl)oxy-2,6- difluoro-phenyl]-2-(2-fluoro- 2-methyl-propyl)-3-methyl- 1,3,4,9-tetrahydropyrido[3,4- b]indole::US20250114338, Example 162

SMILES CCN1CC(Oc2cc(F)c([C@@H]3c4[nH]c5ccccc5c4C[C@@H](C)N3CC(C)(C)F)c(F)c2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731745   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731745((1R,3R)-1-[4-(1- ethylazetidin-3-yl)oxy-2,6- diflu...)
Affinity DataEC50:  0.0530nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
8/22/2025
Entry Details
US Patent