BDBM731787 (1R,3R)-1-[2,6-difluoro-4-[1- (3-fluoropropyl)azetidin-3- yl]oxy-phenyl]-3-methyl-2- methylsulfonyl-1,3,4,9- tetrahydropyrido[3,4-b]indole::US20250114338, Example 202

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(OC3CN(CCCF)C3)cc2F)N1S(C)(=O)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731787   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731787((1R,3R)-1-[2,6-difluoro-4-[1- (3-fluoropropyl)azet...)
Affinity DataEC50:  0.100nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent