BDBM731822 2-fluoro-1-[(1R,3R)-1-[2- fluoro-4-[2-[3- (fluoromethyl)azetidin-1- yl]ethoxy]phenyl]-3-methyl- 1,3,4,9-tetrahydropyrido[3,4- b]indol-2-yl]-2-methyl- propan-1-one::US20250114338, Example 230

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2ccc(OCCN3CC(CF)C3)cc2F)N1C(=O)C(C)(C)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731822   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731822(2-fluoro-1-[(1R,3R)-1-[2- fluoro-4-[2-[3- (fluorom...)
Affinity DataEC50:  0.0680nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
8/22/2025
Entry Details
US Patent