BDBM731915 (1R,3R)-2-(2,2- difluoroethyl)-1-[2,6- difluoro-4-[1-(3- fluoropropyl)azetidin-3- yl]oxy-phenyl]-3-methyl- 1,3,4,9-tetrahydropyrido[3,4- b]indole::US20250114338, Example 303

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(OC3CN(CCCF)C3)cc2F)N1CC(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731915   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731915((1R,3R)-2-(2,2- difluoroethyl)-1-[2,6- difluoro-4-...)
Affinity DataEC50:  0.0480nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent