BDBM732840 N-(4-hydroxyphenyl)-N-[(3-methoxy-2- methyl-phenyl)methyl]-1,2-dimethyl-5-[2- [(3S)-3-(morpholinomethyl)-3,4-dihydro- 1H-isoquinoline-2-carbonyl]-5-nitro- phenyl]pyrrole-3-carboxamide::US20250115577, Compound 61

SMILES COc1cccc(CN(C(=O)c2cc(-c3cc([N+](=O)[O-])ccc3C(=O)N3Cc4ccccc4C[C@H]3CN3CCOCC3)n(C)c2C)c2ccc(O)cc2)c1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 732840   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732840(N-(4-hydroxyphenyl)-N-[(3-methoxy-2- methyl-phenyl...)
Affinity DataIC50: 5nMAssay Description:BPS Bioscience, #50222: 3 ng of BCL-2, 5 μL of 1:100 anti-His Tb-labeled donor, 5 μL of 1:100 Dye-labeled acceptor, 5 L of 1:40 BCL-2 Peptide Ligand,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732840(N-(4-hydroxyphenyl)-N-[(3-methoxy-2- methyl-phenyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:BPS Bioscience, #50223: 10.5 ng of BCL-xL, 5 μL of 1:120 anti-His Tb-labeled donor, 5 μL of 1:120 Dye-labeled acceptor, 5 μL of 1:96 BCL-xL Peptide L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent