BDBM733341 US20250115594, Example 13

SMILES [2H]C([2H])([2H])OC(=O)N/C=C/CCCc1cc(O)c(C(=O)/C(C)=C/c2cnc(Oc3ccc(-c4ccccc4)cc3)s2)c(=O)o1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 733341   

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Staphylococcus aureus)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM733341(US20250115594, Example 13)
Affinity DataIC50: 10nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 17.1, using reaction mixtures containing (20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM733341(US20250115594, Example 13)
Affinity DataIC50: 20nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM733341(US20250115594, Example 13)
Affinity DataIC50: 6.00E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 17.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent