BDBM733415 N-(4-(4-amino- 7-(1- (azepan-4-yl)-1H- pyrazol-4-yl)- 1-methyl- 1H-pyrazolo[4,3- c]pyridin-3-yl)- 2-((S)-1-(4- fluorophenyl) ethoxy) phenyl)-1,1- difluoromethane- sulfonamide::US20250115598, Compound 74

SMILES C[C@H](Oc1cc(-c2nn(C)c3c(-c4cnn(C5CCCNCC5)c4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 733415   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM733415(N-(4-(4-amino- 7-(1- (azepan-4-yl)-1H- pyrazol-4-y...)
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM733415(N-(4-(4-amino- 7-(1- (azepan-4-yl)-1H- pyrazol-4-y...)
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM733415(N-(4-(4-amino- 7-(1- (azepan-4-yl)-1H- pyrazol-4-y...)
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent