BDBM733881 US20250127913, Compound I-83

SMILES CN(Cc1cnc2nc(N)[nH]c(=O)c2n1)c1ccc(C(=O)N[C@@H](CCc2cn(CCOCCOCCOCCOCCOCCOCC(=O)N3CCN(c4ncc(-c5ccc6nc(COc7cccc(N8CCCC8=O)c7)n(Cc7ccccc7OC(F)F)c6c5)cn4)CC3)nn2)C(=O)O)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 733881   

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733881(US20250127913, Compound I-83)
Affinity DataIC50: 5.30nMAssay Description:Table 15: Folate receptor binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733881(US20250127913, Compound I-83)
Affinity DataIC50: 28nMAssay Description:Table 15: TNFα binding was measured in black 96-well plates using a time-resolved FRET assay using a previously described fluorescence acceptor TNFα ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent