BDBM734322 US20250129032, Example 30

SMILES O=C1CN(c2c(O)cc3c(c2F)CCNCC3)S(=O)(=O)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 734322   

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandPNGBDBM734322(US20250129032, Example 30)
Affinity DataIC50: 2.28nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM734322(US20250129032, Example 30)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed