BDBM734336 5-({5-[7-(3-aminopropoxy)quinolin-8-yl]-1H-pyrazol-3-yl}amino)pyrazine-2-carbonitrile::US20250129049, Example 1

SMILES N#Cc4cnc(Nc3cc(c1c(OCCCN)ccc2cccnc12)[nH]n3)cn4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 734336   

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM734336(5-({5-[7-(3-aminopropoxy)quinolin-8-yl]-1H-pyrazol...)
Affinity DataIC50: 0.370nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent