BDBM735481 US20250129103, Compound 68

SMILES Cc7cc(N)nc([C@@H]6Cc5nc(OC[C@@]12CCCN1C[C@H](F)C2)nc(N4CCN(C(=O)/C=C/C3CCN3C)[C@@H](CC#N)C4)c5CC6C)c7C(F)(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 735481   

LigandPNGBDBM735481(US20250129103, Compound 68)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50S for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

LigandPNGBDBM735481(US20250129103, Compound 68)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50S for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent