BDBM736425 4-((1H-pyrazol-1-yl)methyl)-2- methoxy-N-((6-methoxy-2,3- dihydro-1H-inden-5-yl)sulfonyl)benzamide::US20250136553, Compound 5

SMILES COc1cc(Cn2cccn2)ccc1C(=O)NS(=O)(=O)c1cc2c(cc1OC)CCC2

InChI Key InChIKey=IBIYZSOIVWVATA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736425   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736425BDBM736425(4-((1H-pyrazol-1-yl)methyl)-2- methoxy-N-((6-metho...)
Affinity DataIC50: 178nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent