BDBM736440 4-((1H-pyrazol-1-yl)methyl)- N-((5-(tert-butyl)-2- methoxyphenyl)sulfonyl)- 3-ethoxybenzamide::US20250136553, Compound 21

SMILES CCOc1cc(C(=O)NS(=O)(=O)c2cc(C(C)(C)C)ccc2OC)ccc1Cn1cccn1

InChI Key InChIKey=UWDNJLZSEHAUKR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736440   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736440BDBM736440(4-((1H-pyrazol-1-yl)methyl)- N-((5-(tert-butyl)-2-...)
Affinity DataIC50: 28nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent