BDBM736458 4-((1H-pyrazol-1-yl)methyl)- 3-cyclopropyl-N-((2,6- dimethoxyphenyl)sulfonyl)- 2-fluorobenzamide::US20250136553, Compound 40

SMILES COc1cccc(OC)c1S(=O)(=O)NC(=O)c1ccc(Cn2cccn2)c(C2CC2)c1F

InChI Key InChIKey=DRNGCIULJGPZQF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736458   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736458BDBM736458(4-((1H-pyrazol-1-yl)methyl)- 3-cyclopropyl-N-((2,6...)
Affinity DataIC50: 15nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent