BDBM736467 N-((2,6-dimethoxyphenyl)sulfonyl)- 3-methoxy-4-((pyrimidin- 2-yloxy)methyl)benzamide::US20250136553, Compound 50

SMILES COc1cc(C(=O)NS(=O)(=O)c2c(OC)cccc2OC)ccc1COc1ncccn1

InChI Key InChIKey=REQMJROCZYBBDB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736467   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736467BDBM736467(N-((2,6-dimethoxyphenyl)sulfonyl)- 3-methoxy-4-((p...)
Affinity DataIC50: 96nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent