BDBM736490 6-((1H-pyrazol-1-yl)methyl)-N-((2,6- dimethoxyphenyl)sulfonyl)-5-methoxynicotinamide::US20250136553, Compound 202

SMILES COc1cc(C(=O)NS(=O)(=O)c2c(OC)cccc2OC)cnc1Cn1cccn1

InChI Key InChIKey=IDJAAWRTRMVLIL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736490   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736490BDBM736490(6-((1H-pyrazol-1-yl)methyl)-N-((2,6- dimethoxyphen...)
Affinity DataIC50: 104nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent