BDBM736523 5-((1H-pyrazol-1-yl)methyl)-6-methoxy-N-((2-methoxy-6- (trifluoromethoxy)phenyl)sulfonyl)picolinamide::US20250136553, Compound 235

SMILES COc1cccc(OC(F)(F)F)c1S(=O)(=O)NC(=O)c3ccc(Cn2cccn2)c(OC)n3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736523   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandPNGBDBM736523(5-((1H-pyrazol-1-yl)methyl)-6-methoxy-N-((2-methox...)
Affinity DataIC50: 7nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent