BDBM736546 5-((1H-pyrazol-1-yl)methyl)-N-((5-ethyl-2- methoxyphenyl)sulfonyl)-4-methoxypyrimidine-2-carboxamide::US20250136553, Compound 271

SMILES CCc1ccc(OC)c(S(=O)(=O)NC(=O)c2ncc(Cn3cccn3)c(OC)n2)c1

InChI Key InChIKey=MDONTXWNSGMFCO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736546   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736546BDBM736546(5-((1H-pyrazol-1-yl)methyl)-N-((5-ethyl-2- methoxy...)
Affinity DataIC50: 37nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent