BDBM736711 rac-N-(4-amino-4''-fluoro-[1,1''-biphenyl]-3-yl)-4-((1S,3R)-1-oxido-3-phenyl-4,5-dihydro-3H-1λ6-isothiazol-1-yl)benzamide ::US20250136570, Compound 196

SMILES Nc1ccc(-c2ccc(F)cc2)cc1NC(=O)c1ccc([S@]2(=O)=N[C@@H](c3ccccc3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 736711   

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM736711(rac-N-(4-amino-4'-fluoro-[1,1'-biphenyl]-3-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:IC50 determination for HDAC1 and HDAC3—Prior to adding reagents, 50 nL/well of compound were added to Proxiplates using an Echo dispenser instrument ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM736711(rac-N-(4-amino-4'-fluoro-[1,1'-biphenyl]-3-yl)-4-(...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 determination for HDAC1 and HDAC3—Prior to adding reagents, 50 nL/well of compound were added to Proxiplates using an Echo dispenser instrument ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent