BDBM736852 4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)pyridazin-3-yl)-3-methylpiperazin-2-one ::US20250136581, Example 11

SMILES Cc1nnn(-c2ccc(C(F)F)cc2)c1COc1ccc(N2CCNC(=O)C2C)nn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736852   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736852(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.580nMAssay Description:The affinity of the compound to each subtype of GABAA receptor was determined by competing for the binding of 3H-flunitrazepam to HEK293 cells stably...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent