BDBM736975 4-(3-(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)pyridazin-3-yl)-2-oxopiperazin-1-yl)propyl)benzonitrile ::US20250136581, Example 145

SMILES Cc1nnn(-c2ccc(C(F)F)cc2)c1COc1ccc(N2CCN(CCCc3ccc(C#N)cc3)C(=O)C2)nn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736975   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736975(4-(3-(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl...)
Affinity DataKi:  1.27nMAssay Description:The affinity of the compound to each subtype of GABAA receptor was determined by competing for the binding of 3H-flunitrazepam to HEK293 cells stably...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent